NMR Imaging
The Magnetic Resonance division of mediri GmbH develops customized MR Imaging methods for morphologic as well as physiologic imaging questions. The main focus and expertise of the mediri development team thereby lies on state of the art methods for functional and physiologic imaging techniques. This contains the development and implementation of pulse sequences, reconstruction algorithms and post processing methods for all kinds of research objectives in the field of NMR Imaging.
Oxygen Extraction Mapping The MR research team of mediri develops and evaluates methods for physiologic imaging to determine oxygen consumption in tissue. In several research cooperations these methods are used to determine the viability of brain matter.
Oxygen supply is an important parameter for the evaluation of tissue viability and thus of high interest in both cancer diagnosis and therapy. A promising approach followed by the company is to extract information about oxygen extraction from imaging data from specially designed pulse-sequences. The determination of oxygen saturation follows by quantification of the so-called BOLD-effect. Using a model of tissue structure allows to evaluate the susceptibility difference between tissue and venous blood, from which the blood oxygen extraction fraction can be derived indirectly.
Perfusion Imagingmediri has substantial expertise in the development of MR imaging methods and pulse sequences to depict organ perfusion. The company division MR Imaging can offer solutions suitable for many clinical and research settings where diagnostic information on perfusion and blood flow is required.
Ultrasound Imaging- Research in the field of combination of Ultrasound with other imaging modalities
- Motion detection and organ tracking for Motion correction in radiation therapy and MRI
Clinical Studies
- study design for imaging studies in the clinical research setting
- study design pharmacological imaging studies for drug design
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