Morphometric methods
Morphometric methods can be entitled as ‘the work horse for the detection of tissue changes’. Methods such as voxel based morphometry are currently widely used e.g. for studies of local longitudinal changes in brain structures such as atrophy in dementia. Changes can be detected in response to pharmaceuticals or other events as well as due toageing. Feel free to ask us if you are interested in conducting studies using suchmethods and need efficient implementations of suitable protocols and evaluation schemes.
Volumetry
A growing field of research is the volumetric examination of certain body parts to detect volume changes due to diseases or as a reaction to therapy efforts. For this methodology specialized sequences can provide robust measurements and automatic segmentation provides observer bias free volume,area or height measurements.We are glad to assist you with the design of protocols for distortionfree and isometric methods and sophisticated segmentation and evaluation methods for your research problem at hand.
|
|
Relaxometry
T2 and T1 mapping and other relaxometry methods provide a wide range of valuable information aboutdisease related tissue changes.T1 mapping during dynamic contrast agent uptakehave a large value to show microvascularization and exchange between vessels andtissue.
Relaxometry methods can be used  to obtain outcome parameters in clinical studies that are highly comparable between subjects. We will support you with consulting and implementation work if you are in need of such measurements.
Magnetic Transfer Ratio Measurements
Magnetic Transfer Ratio MRI measurements contain valuable information about large molecule content and can be e.g. used to obtain  outcome parameters that reflect tissue degeneration or changes in molecular content. Such methods are used to great benefit in several studies about the progress of diseases like Multiple Sclerosis.
|
