The therapy with ultrasound is an emerging field in medical research. Especially the non invasive and local tissue ablation with high intensity focused ultrasound (HIFU, FUS = focused ultrasound surgery) has a great chance to be established in clinical routine for the treatment of prostate cancer and uterine myoma. Other entities, such as bone tumors, Brain disorders, or the ablation of liver- and kidney tumors are investigated in clinical studies. Diagnostic ultrasound (USgFUS) and Magnetic Resonance Imaging (MRgFUS) are used to guide and monitor this noninvasive therapy.
However, ultrasound has a manifold higher therapeutic potential. Due to its ability to induce thermal and non thermal tissue effects ultrasound can be used e.g. for vascular occlusion, drug delivery, blood-brain barrier disruption or sonothrombolysis.
Recent mediri work focuses on projects to improve MRgFUS treatment of moving abdominal organs such as liver or kidney by US-motion tracking.
The mediri team has over 20 years of experience in therapeutic ultrasound research. An excerpt of our expertise is listed aside:
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- Tissue ablation with high intensity focus ultrasound (HIFU, FUS)
- MR and US guidance in FUS (MRgFUS/USgFUS)
- Ultrasound mediated drug delivery
- Transient opening of the blood-brain barrier
- Sonoporation (Ultrasound mediated transfection)
- Sonothrombolysis (Lysis of blood clots with ultrasound)
- Acoustic cavitation
- Biological effects of ultrasound
- Ultrasound safety in imaging and therapy
- Ultrasound field measurements and quality assurance
- Ultrasound physics
We would be glad to assist you with your technical, in vitro, in vivo, or clinical therapeutic ultrasound project. Please, do not hesitate to contact our US-team.
Some of our customers and cooperation partners:
- German Cancer Research Center (dkfz), Heidelberg
- University Clinic Mannheim, University of Heidelberg
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